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IKKα negatively regulates ASC-dependent inflammasome activation.
Martin, Bradley N; Wang, Chenhui; Willette-Brown, Jami; Herjan, Tomasz; Gulen, Muhammet F; Zhou, Hao; Bulek, Katarzyna; Franchi, Luigi; Sato, Takashi; Alnemri, Emad S; Narla, Goutham; Zhong, Xiao-Ping; Thomas, James; Klinman, Dennis; Fitzgerald, Katherine A; Karin, Michael; Nuñez, Gabriel; Dubyak, George; Hu, Yinling; Li, Xiaoxia.
Afiliación
  • Martin BN; 1] Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA [2] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [3].
  • Wang C; 1] Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA [2].
  • Willette-Brown J; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, USA.
  • Herjan T; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Gulen MF; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Zhou H; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Bulek K; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
  • Franchi L; Comprehensive Cancer Center, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
  • Sato T; Laboratory of Experimental Immunology, National Cancer Institute, Frederick, Maryland 21702, USA.
  • Alnemri ES; Department of Biochemistry and Molecular Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
  • Narla G; Department of Medicine, Institute for Transformative Molecular Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA.
  • Zhong XP; Department of Pediatrics and Immunology, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Thomas J; Department of Pediatric Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
  • Klinman D; Laboratory of Experimental Immunology, National Cancer Institute, Frederick, Maryland 21702, USA.
  • Fitzgerald KA; Division of Infectious Disease and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
  • Karin M; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego, 9500 Gilman Drive, San Diego, California 92093, USA.
  • Nuñez G; Comprehensive Cancer Center, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
  • Dubyak G; Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
  • Hu Y; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, USA.
  • Li X; Department of Immunology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Nat Commun ; 5: 4977, 2014 Sep 30.
Article en En | MEDLINE | ID: mdl-25266676
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Abajo / Quinasa I-kappa B / Proteínas Reguladoras de la Apoptosis / Inflamasomas Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Abajo / Quinasa I-kappa B / Proteínas Reguladoras de la Apoptosis / Inflamasomas Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2014 Tipo del documento: Article