Relationships among psychosocial factors, biomarkers, preeclampsia, and preterm birth in African American women: a pilot.
Appl Nurs Res
; 28(1): e1-6, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-25282477
ABSTRACT
AIM:
To explore the relationships among psychosocial factors (optimism, uncertainty, social support, coping, psychological distress), biomarkers (cortisol, cytokines), preeclampsia, and preterm birth in African American women.METHODS:
Forty-nine pregnant African American women completed psychosocial questionnaires and had blood collected for biomarkers between 26 and 36 weeks of gestation. Birth outcomes were obtained from birth records.RESULTS:
Women reporting higher levels of social support had lower levels of pro-inflammatory cytokines (IL-2, IL-5, and IL-6). Surprisingly, compared with low-risk pregnant women, women diagnosed with preeclampsia reported more optimism and less avoidance, and had lower levels of cortisol and IFN-γ. Similarly, compared to women with full-term birth, women with preterm birth reported higher levels of optimism and lower levels of avoidance, and had lower levels of IL-10.CONCLUSION:
Psychosocial factors influence inflammation and pregnancy outcomes. Close assessment and monitoring of psychosocial factors may contribute to improved pregnancy outcomes.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Preeclampsia
/
Negro o Afroamericano
/
Biomarcadores
/
Nacimiento Prematuro
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Appl Nurs Res
Asunto de la revista:
ENFERMAGEM
Año:
2015
Tipo del documento:
Article