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A new monoclonal antibody DAG-6F4 against human alpha-dystroglycan reveals reduced core protein in some, but not all, dystroglycanopathy patients.
Humphrey, Emma L; Lacey, Erica; Le, Lam T; Feng, Lucy; Sciandra, Francesca; Morris, Charlotte R; Hewitt, Jane E; Holt, Ian; Brancaccio, Andrea; Barresi, Rita; Sewry, Caroline A; Brown, Susan C; Morris, Glenn E.
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  • Humphrey EL; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK.
  • Lacey E; Comparative Biomedical Sciences, Royal Veterinary College, University of London, London, UK.
  • Le LT; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK.
  • Feng L; Dubowitz Neuromuscular Centre, UCL Institute of Child Health, University College London, London, UK.
  • Sciandra F; CNR - Istituto di Chimica del Riconoscimento Molecolare c/o Istituto di Biochimica e Biochimica Clinica, Catholic University, Rome, Italy.
  • Morris CR; Rare Diseases Advisory Group Service for Neuromuscular Diseases, Muscle Immunoanalysis Unit, Dental Hospital, Newcastle upon Tyne, UK.
  • Hewitt JE; Centre for Genetics and Genomics, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Holt I; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK; Institute for Science and Technology in Medicine, Keele University, Keele, UK.
  • Brancaccio A; CNR - Istituto di Chimica del Riconoscimento Molecolare c/o Istituto di Biochimica e Biochimica Clinica, Catholic University, Rome, Italy.
  • Barresi R; Rare Diseases Advisory Group Service for Neuromuscular Diseases, Muscle Immunoanalysis Unit, Dental Hospital, Newcastle upon Tyne, UK.
  • Sewry CA; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK; Dubowitz Neuromuscular Centre, UCL Institute of Child Health, University College London, London, UK.
  • Brown SC; Comparative Biomedical Sciences, Royal Veterinary College, University of London, London, UK.
  • Morris GE; Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK; Institute for Science and Technology in Medicine, Keele University, Keele, UK. Electronic address: glenn.morris@rjah.nhs.uk.
Neuromuscul Disord ; 25(1): 32-42, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25387694
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne / Distroglicanos / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Animals / Child, preschool / Humans / Infant Idioma: En Revista: Neuromuscul Disord Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne / Distroglicanos / Anticuerpos Monoclonales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Animals / Child, preschool / Humans / Infant Idioma: En Revista: Neuromuscul Disord Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido