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Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
Her, Zhisheng; Teng, Terk-Shin; Tan, Jeslin J L; Teo, Teck-Hui; Kam, Yiu-Wing; Lum, Fok-Moon; Lee, Wendy W L; Gabriel, Christelle; Melchiotti, Rossella; Andiappan, Anand K; Lulla, Valeria; Lulla, Aleksei; Win, Mar K; Chow, Angela; Biswas, Subhra K; Leo, Yee-Sin; Lecuit, Marc; Merits, Andres; Rénia, Laurent; Ng, Lisa F P.
Afiliación
  • Her Z; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Teng TS; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Tan JJ; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Teo TH; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
  • Kam YW; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Lum FM; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Lee WW; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.
  • Gabriel C; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Melchiotti R; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore Doctoral School in Translational and Molecular Medicine (DIMET), University of Milano-Bicocca, Milan, Italy.
  • Andiappan AK; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Lulla V; Institute of Technology, University of Tartu, Tartu, Estonia.
  • Lulla A; Institute of Technology, University of Tartu, Tartu, Estonia.
  • Win MK; Institute of Infectious Disease and Epidemiology (IIDE), Tan Tock Seng Hospital, Singapore, Singapore.
  • Chow A; Institute of Infectious Disease and Epidemiology (IIDE), Tan Tock Seng Hospital, Singapore, Singapore.
  • Biswas SK; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Leo YS; Institute of Infectious Disease and Epidemiology (IIDE), Tan Tock Seng Hospital, Singapore, Singapore.
  • Lecuit M; Institut Pasteur, Biology of Infection Unit, Paris, France Inserm U1117, Paris, France Paris Descartes University Sorbonne Paris Cité, Necker-Enfants Malades University Hospital, Institut Imagine, Paris, France.
  • Merits A; Institute of Technology, University of Tartu, Tartu, Estonia.
  • Rénia L; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore.
  • Ng LF; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Singapore Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Institute of Infection and Global Health, University of Liverp
EMBO Mol Med ; 7(1): 24-41, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25452586
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Replicación Viral / Virus Chikungunya / Receptor Toll-Like 3 / Anticuerpos Neutralizantes / Fiebre Chikungunya / Anticuerpos Antivirales Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article País de afiliación: Singapur
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Replicación Viral / Virus Chikungunya / Receptor Toll-Like 3 / Anticuerpos Neutralizantes / Fiebre Chikungunya / Anticuerpos Antivirales Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2015 Tipo del documento: Article País de afiliación: Singapur