Your browser doesn't support javascript.
loading
Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes.
Hett, Erik C; Xu, Hua; Geoghegan, Kieran F; Gopalsamy, Ariamala; Kyne, Robert E; Menard, Carol A; Narayanan, Arjun; Parikh, Mihir D; Liu, Shenping; Roberts, Lee; Robinson, Ralph P; Tones, Michael A; Jones, Lyn H.
Afiliación
  • Hett EC; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Xu H; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Geoghegan KF; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Gopalsamy A; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Kyne RE; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Menard CA; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Narayanan A; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Parikh MD; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Liu S; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Roberts L; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Robinson RP; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Tones MA; §Structural Biology and Biophysics, Worldwide Medicinal Chemistry, ∥Worldwide Medicinal Chemistry, and ⊥Primary Pharmacology Group, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Jones LH; †Worldwide Medicinal Chemistry and ‡Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States.
ACS Chem Biol ; 10(4): 1094-8, 2015 Apr 17.
Article en En | MEDLINE | ID: mdl-25571984
Asunto(s)
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Sulfínicos / Tirosina / Sondas Moleculares / Endorribonucleasas / Inhibidores Enzimáticos Límite: Humans Idioma: En Revista: ACS Chem Biol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Sulfínicos / Tirosina / Sondas Moleculares / Endorribonucleasas / Inhibidores Enzimáticos Límite: Humans Idioma: En Revista: ACS Chem Biol Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos