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PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.
Vasheghani, Faezeh; Zhang, Yue; Li, Ying-Hua; Blati, Meryem; Fahmi, Hassan; Lussier, Bertrand; Roughley, Peter; Lagares, David; Endisha, Helal; Saffar, Bahareh; Lajeunesse, Daniel; Marshall, Wayne K; Rampersaud, Y Raja; Mahomed, Nizar N; Gandhi, Rajiv; Pelletier, Jean-Pierre; Martel-Pelletier, Johanne; Kapoor, Mohit.
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  • Vasheghani F; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Zhang Y; Division of Genetics and Development, Toronto Western Research Institute, University Health Network (UHN), Toronto, Ontario, Canada.
  • Li YH; Division of Genetics and Development, Toronto Western Research Institute, University Health Network (UHN), Toronto, Ontario, Canada.
  • Blati M; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Fahmi H; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Lussier B; Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Quebec, Canada.
  • Roughley P; Genetics Unit, Shriners Hospital, McGill University, Montreal, Quebec, Canada.
  • Lagares D; Pulmonary and Critical Care Unit and Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Massachusetts, USA.
  • Endisha H; Division of Genetics and Development, Toronto Western Research Institute, University Health Network (UHN), Toronto, Ontario, Canada.
  • Saffar B; Division of Genetics and Development, Toronto Western Research Institute, University Health Network (UHN), Toronto, Ontario, Canada.
  • Lajeunesse D; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Marshall WK; Division of Orthopedics, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Rampersaud YR; Division of Orthopedics, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Mahomed NN; Division of Orthopedics, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Gandhi R; Division of Orthopedics, Toronto Western Hospital, Toronto, Ontario, Canada.
  • Pelletier JP; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Martel-Pelletier J; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada.
  • Kapoor M; Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canada Division of Genetics and Development, Toronto Western Research Institute, University Health Network (UHN), Toronto, Ontario, Canada Division of Orthopedics, Toronto Western Hospital, Toro
Ann Rheum Dis ; 74(3): 569-78, 2015 Mar.
Article en En | MEDLINE | ID: mdl-25573665
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cartílago Articular / Osteoartritis de la Rodilla / PPAR gamma / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Ann Rheum Dis Año: 2015 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cartílago Articular / Osteoartritis de la Rodilla / PPAR gamma / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Ann Rheum Dis Año: 2015 Tipo del documento: Article País de afiliación: Canadá