miR-21 regulates triglyceride and cholesterol metabolism in non-alcoholic fatty liver disease by targeting HMGCR.

Sun, Chuanzheng; Huang, Feizhou; Liu, Xunyang; Xiao, Xuefei; Yang, Mingshi; Hu, Gui; Liu, Huaizheng; Liao, Liangkan

Sun, Chuanzheng; Huang, Feizhou; Liu, Xunyang; Xiao, Xuefei; Yang, Mingshi; Hu, Gui; Liu, Huaizheng; Liao, Liangkan.

Afiliación

Sun C; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Huang F; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Liu X; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Xiao X; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Yang M; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Hu G; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Liu H; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Liao L; Department of Emergency Medicine, The Third XiangYa Hospital of Central South University, Changsha, Hunan 410013, P.R. China.

Int J Mol Med ; 35(3): 847-53, 2015 Mar.

Article en En | MEDLINE | ID: mdl-25605429

Asunto(s)

Colesterol/metabolismo; Regulación de la Expresión Génica; Hidroximetilglutaril-CoA Reductasas/genética; MicroARNs/genética; Enfermedad del Hígado Graso no Alcohólico/genética; Enfermedad del Hígado Graso no Alcohólico/metabolismo; Triglicéridos/metabolismo; Regiones no Traducidas 3'; Estudios de Casos y Controles; Células Hep G2; Humanos; Hidroximetilglutaril-CoA Reductasas/química; Hidroximetilglutaril-CoA Reductasas/metabolismo; MicroARNs/química; Interferencia de ARN; ARN Mensajero/química; ARN Mensajero/genética; ARN Mensajero/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triglicéridos / Regulación de la Expresión Génica / Colesterol / MicroARNs / Enfermedad del Hígado Graso no Alcohólico / Hidroximetilglutaril-CoA Reductasas Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Int J Mol Med Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article

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