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Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.
Reschen, Michael E; Gaulton, Kyle J; Lin, Da; Soilleux, Elizabeth J; Morris, Andrew J; Smyth, Susan S; O'Callaghan, Christopher A.
Afiliación
  • Reschen ME; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Lin D; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Soilleux EJ; Nuffield Department of Clinical Laboratory Sciences, University of Oxford and Department of Cellular Pathology, John Radcliffe Hospital, Oxford, United Kingdom.
  • Morris AJ; Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, Lexington, Kentucky, United States of America; Department of Veterans Affairs Medical Center, Lexington, Kentucky, United States of America.
  • Smyth SS; Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, Lexington, Kentucky, United States of America; Department of Veterans Affairs Medical Center, Lexington, Kentucky, United States of America.
  • O'Callaghan CA; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
PLoS Genet ; 11(4): e1005061, 2015 Apr.
Article en En | MEDLINE | ID: mdl-25835000
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Fosfatidato Fosfatasa / Proteína beta Potenciadora de Unión a CCAAT / Epigénesis Genética / Placa Aterosclerótica / Células Espumosas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Fosfatidato Fosfatasa / Proteína beta Potenciadora de Unión a CCAAT / Epigénesis Genética / Placa Aterosclerótica / Células Espumosas Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido