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Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective.
Kaplan, Anna; Gaschler, Michael M; Dunn, Denise E; Colligan, Ryan; Brown, Lewis M; Palmer, Arthur G; Lo, Donald C; Stockwell, Brent R.
Afiliación
  • Kaplan A; Department of Biological Sciences, Columbia University, New York, NY 10027;
  • Gaschler MM; Department of Chemistry, Columbia University, New York, NY 10027;
  • Dunn DE; Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, NC 27710;
  • Colligan R; Department of Biological Sciences, Columbia University, New York, NY 10027; Quantitative Proteomics Center, Columbia University, New York, NY 10027;
  • Brown LM; Department of Biological Sciences, Columbia University, New York, NY 10027; Quantitative Proteomics Center, Columbia University, New York, NY 10027;
  • Palmer AG; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032; and.
  • Lo DC; Center for Drug Discovery and Department of Neurobiology, Duke University Medical Center, Durham, NC 27710;
  • Stockwell BR; Department of Biological Sciences, Columbia University, New York, NY 10027; Department of Chemistry, Columbia University, New York, NY 10027; Howard Hughes Medical Institute and Department of Systems Biology, Columbia University, New York, NY 10027 bstockwell@columbia.edu.
Proc Natl Acad Sci U S A ; 112(17): E2245-52, 2015 Apr 28.
Article en En | MEDLINE | ID: mdl-25848045
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Fármacos Neuroprotectores / Proteína Disulfuro Isomerasas / Cuerpo Estriado / Inhibidores Enzimáticos Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Fármacos Neuroprotectores / Proteína Disulfuro Isomerasas / Cuerpo Estriado / Inhibidores Enzimáticos Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article