The role of Krüppel-like factor 4 in transforming growth factor-ß-induced inflammatory and fibrotic responses in human proximal tubule cells.

Mreich, Ellein; Chen, Xin-Ming; Zaky, Amgad; Pollock, Carol A; Saad, Sonia

Mreich, Ellein; Chen, Xin-Ming; Zaky, Amgad; Pollock, Carol A; Saad, Sonia.

Afiliación

Mreich E; Department of Medicine, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.
Chen XM; Department of Medicine, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.
Zaky A; Department of Medicine, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.
Pollock CA; Department of Medicine, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.
Saad S; Department of Medicine, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.

Clin Exp Pharmacol Physiol ; 42(6): 680-6, 2015 Jun.

Article en En | MEDLINE | ID: mdl-25882815

Asunto(s)

Diabetes Mellitus Experimental/inducido químicamente; Diabetes Mellitus Experimental/metabolismo; Túbulos Renales Proximales/metabolismo; Factores de Transcripción de Tipo Kruppel/fisiología; Factor de Crecimiento Transformador beta1/toxicidad; Animales; Células Cultivadas; Diabetes Mellitus Experimental/patología; Fibrosis/inducido químicamente; Fibrosis/metabolismo; Fibrosis/patología; Humanos; Mediadores de Inflamación/metabolismo; Túbulos Renales Proximales/efectos de los fármacos; Túbulos Renales Proximales/patología; Factor 4 Similar a Kruppel; Ratones; Ratones Noqueados

Palabras clave

Krüppel-like factor 4 (KLF4); diabetic nephropathy; fibrosis; inflammation; proximal tubule; transforming growth factor-beta1 (TGF-ß1)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Factores de Transcripción de Tipo Kruppel / Factor de Crecimiento Transformador beta1 / Túbulos Renales Proximales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Clin Exp Pharmacol Physiol Año: 2015 Tipo del documento: Article País de afiliación: Australia

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