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The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
McHugh, Colleen A; Chen, Chun-Kan; Chow, Amy; Surka, Christine F; Tran, Christina; McDonel, Patrick; Pandya-Jones, Amy; Blanco, Mario; Burghard, Christina; Moradian, Annie; Sweredoski, Michael J; Shishkin, Alexander A; Su, Julia; Lander, Eric S; Hess, Sonja; Plath, Kathrin; Guttman, Mitchell.
Afiliación
  • McHugh CA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Chen CK; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Chow A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Surka CF; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Tran C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • McDonel P; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.
  • Pandya-Jones A; 1] Department of Biological Chemistry, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, University of California Los Angeles, Los Angeles, California 90095, USA [2] Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, Universi
  • Blanco M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Burghard C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Moradian A; Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, California 91125, USA.
  • Sweredoski MJ; Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, California 91125, USA.
  • Shishkin AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Su J; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Lander ES; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.
  • Hess S; Proteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, California 91125, USA.
  • Plath K; 1] Department of Biological Chemistry, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, University of California Los Angeles, Los Angeles, California 90095, USA [2] Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, Universi
  • Guttman M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Nature ; 521(7551): 232-6, 2015 May 14.
Article en En | MEDLINE | ID: mdl-25915022
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Espectrometría de Masas / Transcripción Genética / Cromosoma X / Proteínas Nucleares / Silenciador del Gen / ARN Largo no Codificante / Histona Desacetilasas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nature Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Espectrometría de Masas / Transcripción Genética / Cromosoma X / Proteínas Nucleares / Silenciador del Gen / ARN Largo no Codificante / Histona Desacetilasas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nature Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos