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A novel brain stimulation technology provides compatibility with MRI.
Serano, Peter; Angelone, Leonardo M; Katnani, Husam; Eskandar, Emad; Bonmassar, Giorgio.
Afiliación
  • Serano P; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, U.S.A.
  • Angelone LM; Department of Electrical and Computer Engineering, University of Maryland, College Park, MD, U.S.A.
  • Katnani H; Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD, U.S.A.
  • Eskandar E; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, U.S.A.
  • Bonmassar G; Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD, U.S.A.
Sci Rep ; 5: 9805, 2015 Apr 29.
Article en En | MEDLINE | ID: mdl-25924189
Clinical electrical stimulation systems--such as pacemakers and deep brain stimulators (DBS)--are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Imagen por Resonancia Magnética / Estimulación Encefálica Profunda / Estimulación Eléctrica Límite: Humans Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Imagen por Resonancia Magnética / Estimulación Encefálica Profunda / Estimulación Eléctrica Límite: Humans Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos