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Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase.
Han, SeungHye; Lear, Travis B; Jerome, Jacob A; Rajbhandari, Shristi; Snavely, Courtney A; Gulick, Dexter L; Gibson, Kevin F; Zou, Chunbin; Chen, Bill B; Mallampalli, Rama K.
Afiliación
  • Han S; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Lear TB; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Jerome JA; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Rajbhandari S; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Snavely CA; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Gulick DL; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Gibson KF; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Zou C; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Chen BB; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.
  • Mallampalli RK; Department of Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, Pennsylvania 15213; Department of Cell Biology, Physiology, and Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213; Medical Specialty Service Line, Veterans Affairs Pittsburgh
J Biol Chem ; 290(29): 18124-18133, 2015 Jul 17.
Article en En | MEDLINE | ID: mdl-26037928

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Lipopolisacáridos / Ubiquitina-Proteína Ligasas / Proteínas F-Box / Inflamasomas Límite: Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Lipopolisacáridos / Ubiquitina-Proteína Ligasas / Proteínas F-Box / Inflamasomas Límite: Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article