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Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease.
Irwin, Ronald W; Solinsky, Christine M; Loya, Carlos M; Salituro, Francesco G; Rodgers, Kathleen E; Bauer, Gerhard; Rogawski, Michael A; Brinton, Roberta Diaz.
Afiliación
  • Irwin RW; Department of Pharmacology and Pharmaceutical Science, School of Pharmacy, University of Southern California, Los Angeles, California, United States of America.
  • Solinsky CM; Clinical and Experimental Therapeutics Program, University of Southern California, Los Angeles, California, United States of America.
  • Loya CM; Sage Therapeutics, Cambridge, Massachusetts, United States of America.
  • Salituro FG; Sage Therapeutics, Cambridge, Massachusetts, United States of America.
  • Rodgers KE; Titus Family Department of Clinical Pharmacy and Pharmaceutical Economics & Policy, School of Pharmacy, University of Southern California, Los Angeles, California, United States of America.
  • Bauer G; Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California, United States of America.
  • Rogawski MA; Department of Neurology, School of Medicine, University of California Davis, Sacramento, California, United States of America.
  • Brinton RD; Department of Pharmacology and Pharmaceutical Science, School of Pharmacy, University of Southern California, Los Angeles, California, United States of America; Department of Neurology, Keck School of Medicine, University of Southern California Los Angeles, Los Angeles, California, United states of
PLoS One ; 10(6): e0128313, 2015.
Article en En | MEDLINE | ID: mdl-26039057
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pregnanolona / Evaluación Preclínica de Medicamentos / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pregnanolona / Evaluación Preclínica de Medicamentos / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos