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Discovery of novel purine-based heterocyclic P2X7 receptor antagonists.
Kwak, Seung-Hwa; Lee, Won-Gil; Lee, Yun-Jin; Lee, So-Deok; Kim, Yong-Chul; Ko, Hyojin.
Afiliación
  • Kwak SH; School of Life Sciences, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea.
  • Lee WG; Department of Chemistry, Yale University, New Haven, CT 06520-8107, USA.
  • Lee YJ; Poly Oleffin Elastomer (POE) Project Team, LG Chemistry, 104-1, Moonji-dong, Yuseong-gu, Daejeon 305-738, Republic of Korea.
  • Lee SD; School of Life Sciences, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea.
  • Kim YC; School of Life Sciences, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea; Department of Medical System Engineering (DMSE), Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea. Electronic address: yongchul@gist.
  • Ko H; School of Life Sciences, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea. Electronic address: kohyojin@gist.ac.kr.
Bioorg Chem ; 61: 58-65, 2015 Aug.
Article en En | MEDLINE | ID: mdl-26123174
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Purinas / Antagonistas del Receptor Purinérgico P2X / Compuestos Heterocíclicos Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2015 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Purinas / Antagonistas del Receptor Purinérgico P2X / Compuestos Heterocíclicos Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2015 Tipo del documento: Article