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Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.
Ma, Julian K-C; Drossard, Jürgen; Lewis, David; Altmann, Friedrich; Boyle, Julia; Christou, Paul; Cole, Tom; Dale, Philip; van Dolleweerd, Craig J; Isitt, Valerie; Katinger, Dietmar; Lobedan, Martin; Mertens, Hubert; Paul, Mathew J; Rademacher, Thomas; Sack, Markus; Hundleby, Penelope A C; Stiegler, Gabriela; Stoger, Eva; Twyman, Richard M; Vcelar, Brigitta; Fischer, Rainer.
Afiliación
  • Ma JK; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Drossard J; Fraunhofer IME, Aachen, Germany.
  • Lewis D; RWTH Aachen University, Aachen, Germany.
  • Altmann F; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Boyle J; Department of Chemistry, Universität für Bodenkultur (BOKU), Vienna, Austria.
  • Christou P; Clinical Research Centre, Institute of Biosciences and Medicine, Faculty of Health & Medical Sciences, University of Surrey, Guildford, Surrey, UK.
  • Cole T; Department of Plant Production and Forestry Science, ETSEA, University of Lleida-Agrotecnio Center, Lleida, Spain.
  • Dale P; Institució Catalana de Recerca i Estudis Avançats, Passeig Lluís Companys 23, Barcelona, Spain.
  • van Dolleweerd CJ; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Isitt V; John Innes Centre, Norwich Research Park, Norwich, UK.
  • Katinger D; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Lobedan M; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Mertens H; Polymun Scientific Immunbiologische Forschung GmbH, Klosterneuburg, Austria.
  • Paul MJ; Fraunhofer IME, Aachen, Germany.
  • Rademacher T; RWTH Aachen University, Aachen, Germany.
  • Sack M; Fraunhofer IME, Aachen, Germany.
  • Hundleby PA; RWTH Aachen University, Aachen, Germany.
  • Stiegler G; Molecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London, UK.
  • Stoger E; Fraunhofer IME, Aachen, Germany.
  • Twyman RM; RWTH Aachen University, Aachen, Germany.
  • Vcelar B; Fraunhofer IME, Aachen, Germany.
  • Fischer R; RWTH Aachen University, Aachen, Germany.
Plant Biotechnol J ; 13(8): 1106-20, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26147010
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Control Social Formal / Nicotiana / Aprobación de Drogas / Anticuerpos Monoclonales Tipo de estudio: Clinical_trials / Guideline Límite: Animals / Female / Humans Idioma: En Revista: Plant Biotechnol J Asunto de la revista: BIOTECNOLOGIA / BOTANICA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Control Social Formal / Nicotiana / Aprobación de Drogas / Anticuerpos Monoclonales Tipo de estudio: Clinical_trials / Guideline Límite: Animals / Female / Humans Idioma: En Revista: Plant Biotechnol J Asunto de la revista: BIOTECNOLOGIA / BOTANICA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido