Nucleosome Dancing at the Tempo of Histone Tail Acetylation.
Genes (Basel)
; 6(3): 607-21, 2015 Jul 15.
Article
en En
| MEDLINE
| ID: mdl-26184324
ABSTRACT
The impact of histone acetylation on transcription was revealed over 50 years ago by Allfrey and colleagues. However, it took decades for an understanding of the fine mechanism by which this posttranslational modification affects chromatin structure and promotes transcription. Here, we review breakthroughs linking histone tail acetylation, histone dynamics, and transcription. We also discuss the histone exchange during transcription and highlight the important function of a pool of non-chromatinized histones in chromatin dynamics.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Genes (Basel)
Año:
2015
Tipo del documento:
Article
País de afiliación:
Francia