Passenger Mutations Identified in the Blink of an Eye.

Nechanitzky, Robert; Mak, Tak Wah

Nechanitzky, Robert; Mak, Tak Wah.

Afiliación

Nechanitzky R; The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada.
Mak TW; The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address: tmak@uhnresearch.ca.

Immunity ; 43(1): 9-11, 2015 Jul 21.

Article en En | MEDLINE | ID: mdl-26200008

ABSTRACT

ABSTRACT

Passenger mutations specific to particular mouse strains can distort experimental outcomes. In this issue of Immunity, Vanden Berghe et al. (2015) demonstrate that passenger mutations are frequent in most genetically engineered congenic mice and persist even after extensive backcrossing.

Asunto(s)

Variación Genética/genética; Genoma/genética; Ratones Endogámicos C57BL/genética; Animales

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Genoma / Ratones Endogámicos C57BL Límite: Animals Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Canadá

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