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Development of Selective Covalent Janus Kinase 3 Inhibitors.
Tan, Li; Akahane, Koshi; McNally, Randall; Reyskens, Kathleen M S E; Ficarro, Scott B; Liu, Suhu; Herter-Sprie, Grit S; Koyama, Shohei; Pattison, Michael J; Labella, Katherine; Johannessen, Liv; Akbay, Esra A; Wong, Kwok-Kin; Frank, David A; Marto, Jarrod A; Look, Thomas A; Arthur, J Simon C; Eck, Michael J; Gray, Nathanael S.
Afiliación
  • Tan L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • McNally R; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • Reyskens KM; Division of Cell Signaling and Immunology, College of Life Sciences, University of Dundee , Dundee DD1 5EH. U.K.
  • Ficarro SB; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • Pattison MJ; Division of Cell Signaling and Immunology, College of Life Sciences, University of Dundee , Dundee DD1 5EH. U.K.
  • Johannessen L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • Marto JA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • Arthur JS; Division of Cell Signaling and Immunology, College of Life Sciences, University of Dundee , Dundee DD1 5EH. U.K.
  • Eck MJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
  • Gray NS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.
J Med Chem ; 58(16): 6589-606, 2015 Aug 27.
Article en En | MEDLINE | ID: mdl-26258521
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Janus Quinasa 3 / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Janus Quinasa 3 / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos