Self-selected intensity exercise in the treatment of major depression: A pragmatic RCT.
Int J Psychiatry Clin Pract
; 19(4): 266-75, 2015.
Article
en En
| MEDLINE
| ID: mdl-26265421
ABSTRACT
OBJECTIVE:
The purpose of the study was to determine the therapeutic effect of physical exercise for patients with unipolar depression. Participants took part in an 8-week walking/running aerobic exercise program at a local sports club.METHODS:
Forty-six outpatients aged 18-65 years and diagnosed with mild to severe depression (ICD-10 criteria) were randomly assigned to an intervention group or wait list. Treatment as usual was continued. The Hamilton Rating Scale for Depression (HRSD-17) served as the main outcome measure. Secondary outcome measures were Beck Depression Inventory (BDI-II), Fitness Index (FI), and VO(2) max as estimated by Urho Kaleka Kekkonen or UKK 2-km Walk Test.RESULTS:
Out of forty-six participants, 24% dropped out. Participants attended 58% of exercise sessions. All randomized participants were included in intention-to-treat (ITT) analysis. Analysis of covariance or ANCOVA showed a large reduction of depressive symptoms in HRSD-17 scores (Cohen's d 1.8; mean change 8.2, p < .0001). BDI-II (Cohen's d 0.50; mean change 4.7, p = 0.09), FI scores (Cohen's d 0.27; mean change 5.3, p = 0.08), and VO2 max did not change significantly.CONCLUSIONS:
We observed a large and clinically significant change in HRSD-17 scores. Moderate changes in BDI-II scores without clinical significance and small changes in physical fitness assessments were observed.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Evaluación de Resultado en la Atención de Salud
/
Trastorno Depresivo Mayor
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Terapia por Ejercicio
Tipo de estudio:
Clinical_trials
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Psychiatry Clin Pract
Año:
2015
Tipo del documento:
Article
País de afiliación:
Alemania