Unrealistic representations of "the self": A cognitive neuroscience assessment of anosognosia for memory deficit.
Conscious Cogn
; 37: 160-77, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26397037
ABSTRACT
Three cognitive components may play a crucial role in both memory awareness and in anosognosia for memory deficit (AMD) (1) a personal data base (PDB), i.e., a memory store that contains "semantic" representations about the self, (2) monitoring processes (MPs) and (3) an explicit evaluation system (EES), or comparator, that assesses and binds the representations stored in the PDB with information obtained from the environment. We compared both the behavior and the functional connectivity (as assessed by resting-state fMRI) of AMD patients with aware patients and healthy controls. We found that AMD is associated with an impoverished PDB, while MPs are necessary to successfully update the PDB. AMD was associated with reduced functional connectivity within both the default-mode network and in a network that includes the left lateral temporal cortex, the hippocampus and the insula. The reduced connectivity between the hippocampus and the insular cortex was correlated with AMD severity.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Corteza Cerebral
/
Agnosia
/
Ego
/
Memoria a Largo Plazo
/
Trastornos de la Memoria
/
Red Nerviosa
Límite:
Aged
/
Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Conscious Cogn
Asunto de la revista:
PSICOFISIOLOGIA
/
PSICOLOGIA
Año:
2015
Tipo del documento:
Article