TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells.

Finch-Edmondson, Megan L; Strauss, Robyn P; Passman, Adam M; Sudol, Marius; Yeoh, George C; Callus, Bernard A

Finch-Edmondson, Megan L; Strauss, Robyn P; Passman, Adam M; Sudol, Marius; Yeoh, George C; Callus, Bernard A.

Afiliación

Finch-Edmondson ML; From the School of Chemistry and Biochemistry, University of Western Australia, WA 6009, Australia, Department of Physiology, NUS Yong Loo Lin School of Medicine and Mechanobiology Institute (MBI), National University of Singapore, Singapore 117411, and phsmlf@nus.edu.sg.
Strauss RP; From the School of Chemistry and Biochemistry, University of Western Australia, WA 6009, Australia, Centre for Medical Research, The Harry Perkins Institute of Medical Research, WA 6009, Australia.
Passman AM; From the School of Chemistry and Biochemistry, University of Western Australia, WA 6009, Australia, Centre for Medical Research, The Harry Perkins Institute of Medical Research, WA 6009, Australia.
Sudol M; Department of Physiology, NUS Yong Loo Lin School of Medicine and Mechanobiology Institute (MBI), National University of Singapore, Singapore 117411, and Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore 138673.
Yeoh GC; From the School of Chemistry and Biochemistry, University of Western Australia, WA 6009, Australia, Centre for Medical Research, The Harry Perkins Institute of Medical Research, WA 6009, Australia.
Callus BA; From the School of Chemistry and Biochemistry, University of Western Australia, WA 6009, Australia, School of Health Sciences, The University of Notre Dame Australia, WA 6959, Australia.

J Biol Chem ; 290(46): 27928-38, 2015 Nov 13.

Article en En | MEDLINE | ID: mdl-26432639

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/metabolismo; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Fosfoproteínas/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Animales; Apoptosis; Carcinogénesis/genética; Carcinogénesis/metabolismo; Proteínas de Ciclo Celular; Proliferación Celular; Técnicas de Silenciamiento del Gen; Glucógeno Sintasa Quinasa 3/metabolismo; Proteínas HSP90 de Choque Térmico/metabolismo; Células HeLa; Humanos; Ratones; Células 3T3 NIH; Fosfoproteínas/genética; Complejo de la Endopetidasa Proteasomal/metabolismo; Proteolisis; Transactivadores; Factores de Transcripción; Proteínas Coactivadoras Transcripcionales con Motivo de Unión a PDZ; Proteínas Señalizadoras YAP

Palabras clave

Hippo pathway; glycogen synthase kinase 3 (GSK-3); post-transcriptional regulation; protein degradation; transcriptional coactivator with PDZ-binding motif (TAZ); yes-associated protein (YAP)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Péptidos y Proteínas de Señalización Intracelular / Proteínas Adaptadoras Transductoras de Señales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

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