Simultaneous and rapid determination of gefitinib, erlotinib and afatinib plasma levels using liquid chromatography/tandem mass spectrometry in patients with non-small-cell lung cancer.

Hayashi, Hideki; Kita, Yutaro; Iihara, Hirotoshi; Yanase, Koumei; Ohno, Yasushi; Hirose, Chiemi; Yamada, Maya; Todoroki, Kenichiro; Kitaichi, Kiyoyuki; Minatoguchi, Shinya; Itoh, Yoshinori; Sugiyama, Tadashi

Hayashi, Hideki; Kita, Yutaro; Iihara, Hirotoshi; Yanase, Koumei; Ohno, Yasushi; Hirose, Chiemi; Yamada, Maya; Todoroki, Kenichiro; Kitaichi, Kiyoyuki; Minatoguchi, Shinya; Itoh, Yoshinori; Sugiyama, Tadashi.

Afiliación

Hayashi H; Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan.
Kita Y; Department of Pharmacy, Gifu University Hospital, Gifu, Japan.
Iihara H; Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan.
Yanase K; Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan.
Ohno Y; Department of Pharmacy, Gifu University Hospital, Gifu, Japan.
Hirose C; Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
Yamada M; Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
Todoroki K; Department of Pharmacy, Gifu University Hospital, Gifu, Japan.
Kitaichi K; Department of Pharmacy, Gifu University Hospital, Gifu, Japan.
Minatoguchi S; Department of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
Itoh Y; Laboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu, Japan.
Sugiyama T; Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.

Biomed Chromatogr ; 30(7): 1150-1154, 2016 Jul.

Article en En | MEDLINE | ID: mdl-26525154

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Clorhidrato de Erlotinib/sangre; Neoplasias Pulmonares/tratamiento farmacológico; Quinazolinas/sangre; Afatinib; Calibración; Carcinoma de Pulmón de Células no Pequeñas/sangre; Cromatografía Liquida/métodos; Gefitinib; Humanos; Límite de Detección; Neoplasias Pulmonares/sangre; Espectrometría de Masas en Tándem/métodos

Palabras clave

LC-MS/MS; afatinib; erlotinib; gefitinib; therapeutic drug monitoring

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinazolinas / Carcinoma de Pulmón de Células no Pequeñas / Clorhidrato de Erlotinib / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Biomed Chromatogr Año: 2016 Tipo del documento: Article País de afiliación: Japón

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