Combination wt-p53 and MicroRNA-125b Transfection in a Genetically Engineered Lung Cancer Model Using Dual CD44/EGFR-targeting Nanoparticles.

Talekar, Meghna; Trivedi, Malav; Shah, Parin; Ouyang, Qijun; Oka, Adwait; Gandham, Srujan; Amiji, Mansoor M

Talekar, Meghna; Trivedi, Malav; Shah, Parin; Ouyang, Qijun; Oka, Adwait; Gandham, Srujan; Amiji, Mansoor M.

Afiliación

Talekar M; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Trivedi M; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Shah P; Current address: Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, Davie, Florida, USA.
Ouyang Q; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Oka A; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Gandham S; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.
Amiji MM; Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, USA.

Mol Ther ; 24(4): 759-69, 2016 Apr.

Article en En | MEDLINE | ID: mdl-26686386

Asunto(s)

Ácido Hialurónico/administración & dosificación; Neoplasias Pulmonares/terapia; MicroARNs/genética; Proteínas Proto-Oncogénicas p21(ras)/genética; Proteína p53 Supresora de Tumor/genética; Animales; Apoptosis; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Terapia Combinada; Receptores ErbB/metabolismo; Ingeniería Genética; Terapia Genética; Humanos; Receptores de Hialuranos/metabolismo; Ácido Hialurónico/química; Neoplasias Pulmonares/genética; Ratones; Nanopartículas/química; Neoplasias Experimentales; Plásmidos/genética; Transfección

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas p21(ras) / MicroARNs / Ácido Hialurónico / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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