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Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation.
Mazzola, Maria Antonietta; Raheja, Radhika; Murugaiyan, Gopal; Rajabi, Hasan; Kumar, Deepak; Pertel, Thomas; Regev, Keren; Griffin, Russell; Aly, Lilian; Kivisakk, Pia; Nejad, Parham; Patel, Bonny; Gwanyalla, Nguendab; Hei, Hillary; Glanz, Bonnie; Chitnis, Tanuja; Weiner, Howard L; Gandhi, Roopali.
Afiliación
  • Mazzola MA; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. mamazzola@partners.org.
  • Raheja R; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. rsuresh@partners.org.
  • Murugaiyan G; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. mgopal@rics.bwh.harvard.edu.
  • Rajabi H; Dana Farber Cancer Institute, Boston, MA, 02115, USA. Hasan_Rajabi@dfci.harvard.edu.
  • Kumar D; Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA. Deepakkjaiswal@gmail.com.
  • Pertel T; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. tpertel@gmail.com.
  • Regev K; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. KREGEV@PARTNERS.ORG.
  • Griffin R; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. RGRIFFIN5@PARTNERS.ORG.
  • Aly L; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. lilian.m.aly@gmail.com.
  • Kivisakk P; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. pkivisakk@rics.bwh.harvard.edu.
  • Nejad P; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. pnejad@broadinstitute.org.
  • Patel B; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. bonnypat@gmail.com.
  • Gwanyalla N; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. guen.gwanyalla@gmail.com.
  • Hei H; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. Hillary.hey@gmail.com.
  • Glanz B; Partners MS Center, Brigham and Women's Hospital, 1 Brookline Place, Brookline, MA, 02445, USA. bglanz@partners.org.
  • Chitnis T; Partners MS Center, Brigham and Women's Hospital, 1 Brookline Place, Brookline, MA, 02445, USA. tchitnis@rics.bwh.harvard.edu.
  • Weiner HL; Brigham and Women's Hospital, Ann Romney Center for Neurologic Diseases, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA. hweiner@rics.bwh.harvard.edu.
  • Gandhi R; Partners MS Center, Brigham and Women's Hospital, 1 Brookline Place, Brookline, MA, 02445, USA. hweiner@rics.bwh.harvard.edu.
J Neuroinflammation ; 12: 245, 2015 Dec 30.
Article en En | MEDLINE | ID: mdl-26714756
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Regulación hacia Arriba / Factor 1 de Transcripción de Linfocitos T / Clorhidrato de Fingolimod / Inmunosupresores / Esclerosis Múltiple Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Regulación hacia Arriba / Factor 1 de Transcripción de Linfocitos T / Clorhidrato de Fingolimod / Inmunosupresores / Esclerosis Múltiple Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Neuroinflammation Asunto de la revista: NEUROLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos