TIMP3 regulates osteosarcoma cell migration, invasion, and chemotherapeutic resistances.

Han, Xiu-Guo; Li, Yan; Mo, Hui-Min; Li, Kang; Lin, Du; Zhao, Chang-Qing; Zhao, Jie; Tang, Ting-Ting

Han, Xiu-Guo; Li, Yan; Mo, Hui-Min; Li, Kang; Lin, Du; Zhao, Chang-Qing; Zhao, Jie; Tang, Ting-Ting.

Afiliación

Han XG; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China.
Li Y; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China.
Mo HM; Institution of Hematology, Xuzhou Medical College, Department of Hematology, The Affiliated Hospital of Xuzhou Medical College, Jiangsu Province, China.
Li K; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China.
Lin D; Department of Orthopedic Surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhao CQ; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China.
Zhao J; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China. medzhaojie@163.com.
Tang TT; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Zhizaoju Road 639, Shanghai, 200011, China. tingtingtang@hotmail.com.

Tumour Biol ; 37(7): 8857-67, 2016 Jul.

Article en En | MEDLINE | ID: mdl-26749283

Asunto(s)

Movimiento Celular/genética; Resistencia a Antineoplásicos/genética; Invasividad Neoplásica/genética; Osteosarcoma/genética; Osteosarcoma/patología; Inhibidor Tisular de Metaloproteinasa-3/genética; Caspasa 3/genética; Línea Celular Tumoral; Supervivencia Celular/genética; Cisplatino/farmacología; Regulación hacia Abajo/genética; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Metaloproteinasa 1 de la Matriz/genética; Metaloproteinasa 2 de la Matriz/genética; Invasividad Neoplásica/patología; Osteosarcoma/tratamiento farmacológico; Proteínas Proto-Oncogénicas c-akt/genética; Proteínas Proto-Oncogénicas c-bcl-2/genética; Transducción de Señal/genética; Regulación hacia Arriba/genética; Proteína X Asociada a bcl-2/genética

Palabras clave

Cisplatin sensitivity; Invasion; Migration; Osteosarcoma; TIMP3

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteosarcoma / Movimiento Celular / Resistencia a Antineoplásicos / Inhibidor Tisular de Metaloproteinasa-3 / Invasividad Neoplásica Límite: Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: China

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