Endoplasmic reticulum stress-mediated upregulation of miR-29a enhances sensitivity to neuronal apoptosis.

Nolan, Katie; Walter, Franziska; Tuffy, Liam P; Poeschel, Simone; Gallagher, Ross; Haunsberger, Stefan; Bray, Isabella; Stallings, Raymond L; Concannon, Caoimhín G; Prehn, Jochen H M

Nolan, Katie; Walter, Franziska; Tuffy, Liam P; Poeschel, Simone; Gallagher, Ross; Haunsberger, Stefan; Bray, Isabella; Stallings, Raymond L; Concannon, Caoimhín G; Prehn, Jochen H M.

Afiliación

Nolan K; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Walter F; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Tuffy LP; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Poeschel S; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Gallagher R; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Haunsberger S; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Bray I; Cancer Genetics, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Stallings RL; Cancer Genetics, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Concannon CG; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.
Prehn JH; Centre for the Study of Neurological Disorders and Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin, 2, Ireland.

Eur J Neurosci ; 43(5): 640-52, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26750440

Asunto(s)

Apoptosis; Estrés del Retículo Endoplásmico; MicroARNs/genética; Neuronas/metabolismo; Regulación hacia Arriba; Factor de Transcripción Activador 4/genética; Factor de Transcripción Activador 4/metabolismo; Animales; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; Células Cultivadas; Células HeLa; Humanos; Ratones; Ratones Endogámicos C57BL; Proteína 1 de la Secuencia de Leucemia de Células Mieloides/genética; Proteína 1 de la Secuencia de Leucemia de Células Mieloides/metabolismo; Proteínas Supresoras de Tumor/genética; Proteínas Supresoras de Tumor/metabolismo

Palabras clave

BCL-2 proteins; cell death; cortical neurons; endoplasmic reticulum (ER) stress; microRNA

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Arriba / Apoptosis / MicroARNs / Estrés del Retículo Endoplásmico / Neuronas Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Eur J Neurosci Asunto de la revista: NEUROLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Irlanda

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google