Selective Inhibition of Aggregation and Toxicity of a Tau-Derived Peptide using Its Glycosylated Analogues.

Frenkel-Pinter, Moran; Richman, Michal; Belostozky, Anna; Abu-Mokh, Amjaad; Gazit, Ehud; Rahimipour, Shai; Segal, Daniel

Frenkel-Pinter, Moran; Richman, Michal; Belostozky, Anna; Abu-Mokh, Amjaad; Gazit, Ehud; Rahimipour, Shai; Segal, Daniel.

Afiliación

Frenkel-Pinter M; Department Molecular Microbiology and Biotechnology, and the Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel Aviv, 69978, Israel.
Richman M; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel.
Belostozky A; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel.
Abu-Mokh A; Department Molecular Microbiology and Biotechnology, and the Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel Aviv, 69978, Israel.
Gazit E; Department Molecular Microbiology and Biotechnology, and the Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel Aviv, 69978, Israel. dsegal@post.tau.ac.il.
Rahimipour S; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel. rahimis@biu.ac.il.
Segal D; Department Molecular Microbiology and Biotechnology, and the Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel Aviv, 69978, Israel. ehudg@post.tau.ac.il.

Chemistry ; 22(17): 5945-52, 2016 Apr 18.

Article en En | MEDLINE | ID: mdl-26891276

Asunto(s)

Amiloide/antagonistas & inhibidores; Amiloide/química; Oligopéptidos/química; Péptidos/química; Proteínas tau/química; Secuencia de Aminoácidos; Amiloide/metabolismo; Glicosilación; Humanos; Oligopéptidos/metabolismo; Péptidos/metabolismo; Procesamiento Proteico-Postraduccional; Estructura Secundaria de Proteína; Proteínas tau/metabolismo

Palabras clave

PHF6; amyloid formation; glycopeptides; glycosylation; protein and peptide aggregation

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligopéptidos / Péptidos / Proteínas tau / Amiloide Límite: Humans Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Israel

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google