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Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Accelerates Pathogen Identification and May Confer Benefit in the Outcome of Peritoneal Dialysis-Related Peritonitis.
Lin, Wei-Hung; Hwang, Jyh-Chang; Tseng, Chin-Chung; Chang, Yu-Tzu; Wu, An-Bang; Yan, Jing-Jou; Wu, Jiunn-Jong; Wang, Ming-Cheng.
Afiliación
  • Lin WH; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Hwang JC; Division of Nephrology, Chi Mei Medical Center, Tainan, Taiwan.
  • Tseng CC; Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
  • Chang YT; Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
  • Wu AB; Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
  • Yan JJ; Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Wu JJ; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Biotechnology and Laboratory Science in Medicine, School of Biomedical Science and Engineering, National Yang-Ming University, Taipei, Taiwan jjwu@mail.ncku.e
  • Wang MC; Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan jjwu@mail.ncku.edu.tw wangmc@mail.ncku.edu.tw.
J Clin Microbiol ; 54(5): 1381-3, 2016 05.
Article en En | MEDLINE | ID: mdl-26912750
ABSTRACT
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean ± standard deviation, 5.2 ± 4.8 days versus 8.2 ± 4.5 days, P = 0.001).
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Peritonitis / Técnicas Microbiológicas / Diálisis Peritoneal / Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Clin Microbiol Año: 2016 Tipo del documento: Article País de afiliación: Taiwán
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Peritonitis / Técnicas Microbiológicas / Diálisis Peritoneal / Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción Tipo de estudio: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: J Clin Microbiol Año: 2016 Tipo del documento: Article País de afiliación: Taiwán