Equivalency challenge: Evaluation of Lipodox® as the generic equivalent for Doxil® in a human ovarian cancer orthotropic mouse model.

Smith, Judith A; Mathew, Lata; Burney, Maryam; Nyshadham, Pranavanand; Coleman, Robert L

Smith, Judith A; Mathew, Lata; Burney, Maryam; Nyshadham, Pranavanand; Coleman, Robert L.

Afiliación

Smith JA; Department of Gynecology, Obstetrics & Reproductive Sciences, University of Texas Health Science Center Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA; Department of Pharmacy, UTHealth-Memorial Hermann Hospital Cancer Center, 6400 Fannin Street, Suite 2900,Houston, TX 7703
Mathew L; Department of Gynecology, Obstetrics & Reproductive Sciences, University of Texas Health Science Center Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.
Burney M; Department of Gynecology, Obstetrics & Reproductive Sciences, University of Texas Health Science Center Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.
Nyshadham P; Department of Gynecology, Obstetrics & Reproductive Sciences, University of Texas Health Science Center Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.
Coleman RL; Department of Gynecologic Oncology & Reproductive Medicine, The University of Texas MD Anderson Cancer Center, 1144 Pressler St, Houston, TX 77030, USA.

Gynecol Oncol ; 141(2): 357-363, 2016 05.

Article en En | MEDLINE | ID: mdl-26946092

Asunto(s)

Doxorrubicina/análogos & derivados; Neoplasias Ováricas/tratamiento farmacológico; Neoplasias Ováricas/metabolismo; Animales; Antibióticos Antineoplásicos/farmacocinética; Antibióticos Antineoplásicos/farmacología; Línea Celular Tumoral; Doxorrubicina/farmacocinética; Doxorrubicina/farmacología; Femenino; Humanos; Ratones; Ratones Desnudos; Polietilenglicoles/farmacocinética; Polietilenglicoles/farmacología; Distribución Aleatoria; Equivalencia Terapéutica; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Bioequivalence; Doxil; Doxorubicin; Lipodox; Liposomal; Microdialysis; Ovarian cancer

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Doxorrubicina Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Año: 2016 Tipo del documento: Article

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