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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
Cheng, Shih-Chin; Scicluna, Brendon P; Arts, Rob J W; Gresnigt, Mark S; Lachmandas, Ekta; Giamarellos-Bourboulis, Evangelos J; Kox, Matthijs; Manjeri, Ganesh R; Wagenaars, Jori A L; Cremer, Olaf L; Leentjens, Jenneke; van der Meer, Anne J; van de Veerdonk, Frank L; Bonten, Marc J; Schultz, Marcus J; Willems, Peter H G M; Pickkers, Peter; Joosten, Leo A B; van der Poll, Tom; Netea, Mihai G.
Afiliación
  • Cheng SC; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Scicluna BP; Center of Experimental &Molecular Medicine, Division of Infectious Diseases, Amsterdam Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • Arts RJ; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Gresnigt MS; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Lachmandas E; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, University of Athens, Medical School, Athens, Greece.
  • Kox M; Department of Intensive Care and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Manjeri GR; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Wagenaars JA; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
  • Cremer OL; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Leentjens J; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
  • van der Meer AJ; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van de Veerdonk FL; Department of Intensive Care and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Bonten MJ; Center of Experimental &Molecular Medicine, Division of Infectious Diseases, Amsterdam Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • Schultz MJ; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Willems PH; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Pickkers P; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Joosten LA; Department of Intensive Care Medicine Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • van der Poll T; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Netea MG; Department of Intensive Care and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
Nat Immunol ; 17(4): 406-13, 2016 Apr.
Article en En | MEDLINE | ID: mdl-26950237
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Monocitos / Citocinas / Sepsis / Endotoxemia / Metabolismo Energético / Tolerancia Inmunológica / Inmunidad Innata / Macrófagos Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Monocitos / Citocinas / Sepsis / Endotoxemia / Metabolismo Energético / Tolerancia Inmunológica / Inmunidad Innata / Macrófagos Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos