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Safety, tolerability, efficacy and pharmacodynamics of the selective JAK1 inhibitor GSK2586184 in patients with systemic lupus erythematosus.
Kahl, L; Patel, J; Layton, M; Binks, M; Hicks, K; Leon, G; Hachulla, E; Machado, D; Staumont-Sallé, D; Dickson, M; Condreay, L; Schifano, L; Zamuner, S; van Vollenhoven, R F.
Afiliación
  • Kahl L; 1 Clinical Development in Infectious Diseases, GSK, Uxbridge, UK.
  • Patel J; 2 Immuno-Inflammation Therapeutic Area Unit, GSK, Stevenage, UK.
  • Layton M; 2 Immuno-Inflammation Therapeutic Area Unit, GSK, Stevenage, UK.
  • Binks M; 3 Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA.
  • Hicks K; 4 Clinical Statistics Medicines Research Centre, GSK, Stevenage, UK.
  • Leon G; 5 Instituto de Ginecologia y Reproduccion, Lima, Peru.
  • Hachulla E; 6 Claude Huriez Hospital, University of Lille, FHU IMMINeNT, Lille, France.
  • Machado D; 7 Instituto Centralizado de Asistencia e Investigacion Clinica Integral, CAICI, Rosario, Santa Fe, Argentina.
  • Staumont-Sallé D; 6 Claude Huriez Hospital, University of Lille, FHU IMMINeNT, Lille, France.
  • Dickson M; 2 Immuno-Inflammation Therapeutic Area Unit, GSK, Stevenage, UK.
  • Condreay L; 8 GSK, Research Triangle Park, NC, USA.
  • Schifano L; 8 GSK, Research Triangle Park, NC, USA.
  • Zamuner S; 9 Clinical Pharmacology Modelling and Simulation Department, GSK, Uxbridge, UK.
  • van Vollenhoven RF; 10 Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden.
Lupus ; 25(13): 1420-1430, 2016 Nov.
Article en En | MEDLINE | ID: mdl-27055521
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Azetidinas / Triazoles / Janus Quinasa 1 / Lupus Eritematoso Sistémico Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lupus Asunto de la revista: REUMATOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Azetidinas / Triazoles / Janus Quinasa 1 / Lupus Eritematoso Sistémico Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lupus Asunto de la revista: REUMATOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido