Monocytes Take Their Own Path to IL-1ß.

Elliott, Eric I; Sutterwala, Fayyaz S

Elliott, Eric I; Sutterwala, Fayyaz S.

Afiliación

Elliott EI; Interdisciplinary Graduate Program in Molecular and Cellular Biology, University of Iowa, Iowa City, IA 52242, USA; Medical Scientist Training Program, University of Iowa, Iowa City, IA 52242, USA.
Sutterwala FS; Interdisciplinary Graduate Program in Molecular and Cellular Biology, University of Iowa, Iowa City, IA 52242, USA; Medical Scientist Training Program, University of Iowa, Iowa City, IA 52242, USA; Division of Infectious Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: fayyaz.sutterwala@cshs.org.

Immunity ; 44(4): 713-5, 2016 Apr 19.

Article en En | MEDLINE | ID: mdl-27096310

RESUMEN

Generally, two signals are required to activate the NLRP3 inflammasome. In this issue of Immunity, Hornung and colleagues (2016) describe an alternative inflammasome activation pathway in human monocytes triggering activation of the NLRP3 inflammasome in response to a single stimulus.

Asunto(s)

Caspasa 1/metabolismo; Monocitos/metabolismo; Proteínas Portadoras/metabolismo; Humanos; Inflamasomas/metabolismo; Interleucina-1beta/metabolismo; Especies Reactivas de Oxígeno/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Monocitos / Caspasa 1 Límite: Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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