Serial assessment of functional recovery following nerve injury using implantable thin-film wireless nerve stimulators.
Muscle Nerve
; 54(6): 1114-1119, 2016 12.
Article
en En
| MEDLINE
| ID: mdl-27105137
ABSTRACT
INTRODUCTION:
Comprehensive assessment of the time course of functional recovery following peripheral nerve repair is critical for surgical management of peripheral nerve injuries. This study describes the design and implementation of a novel implantable wireless nerve stimulator capable of repeatedly interfacing peripheral nerve tissue and providing serial evaluation of functional recovery postoperatively.METHODS:
Thin-film wireless implants were fabricated and subcutaneously implanted into Lewis rats. Wireless implants were used to serially stimulate rat sciatic nerve and assess functional recovery over 3 months following various nerve injuries.RESULTS:
Wireless stimulators demonstrated consistent performances over 3 months in vivo and successfully facilitated serial assessment of nerve and muscle function following nerve crush and nerve transection injuries.CONCLUSIONS:
This study highlights the ability of implantable wireless nerve stimulators to provide a unique view into the time course of functional recovery in multiple motor targets. Muscle Nerve 54 1114-1119, 2016.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Telemetría
/
Terapia por Estimulación Eléctrica
/
Recuperación de la Función
/
Neuropatía Ciática
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Muscle Nerve
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos