hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico - In Vitro Screening.

Kratz, Jadel M; Mair, Christina E; Oettl, Sarah K; Saxena, Priyanka; Scheel, Olaf; Schuster, Daniela; Hering, Steffen; Rollinger, Judith M

Kratz, Jadel M; Mair, Christina E; Oettl, Sarah K; Saxena, Priyanka; Scheel, Olaf; Schuster, Daniela; Hering, Steffen; Rollinger, Judith M.

Afiliación

Kratz JM; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Mair CE; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Oettl SK; Institute of Pharmacy/Pharmacognosy, University of Innsbruck, Innsbruck, Austria.
Saxena P; Department of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.
Scheel O; Cytocentrics Bioscience GmbH, Rostock, Germany.
Schuster D; Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Hering S; Department of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.
Rollinger JM; Department of Pharmacognosy, University of Vienna, Vienna, Austria.

Planta Med ; 82(11-12): 1009-15, 2016 Jul.

Article en En | MEDLINE | ID: mdl-27145237

Asunto(s)

Alcaloides/farmacología; Cephaelis/química; Canales de Potasio Éter-A-Go-Go/antagonistas & inhibidores; Ipeca/farmacología; Alcaloides/química; Alcaloides/aislamiento & purificación; Animales; Simulación por Computador; Humanos; Ipeca/química; Estructura Molecular; Xenopus laevis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cephaelis / Alcaloides / Canales de Potasio Éter-A-Go-Go / Ipeca Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Planta Med Año: 2016 Tipo del documento: Article País de afiliación: Austria

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