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Small-molecule binding of the axin RGS domain promotes ß-catenin and Ras degradation.
Cha, Pu-Hyeon; Cho, Yong-Hee; Lee, Sang-Kyu; Lee, JaeHeon; Jeong, Woo-Jeong; Moon, Byoung-San; Yun, Ji-Hye; Yang, Jee Sun; Choi, Sooho; Yoon, Juyong; Kim, Hyun-Yi; Kim, Mi-Yeon; Kaduwal, Saluja; Lee, Weontae; Min, Do Sik; Kim, Hoguen; Han, Gyoonhee; Choi, Kang-Yell.
Afiliación
  • Cha PH; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Cho YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Lee SK; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Lee J; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Jeong WJ; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Moon BS; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Yun JH; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Yang JS; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Choi S; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Yoon J; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Kim HY; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Kim MY; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Kaduwal S; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Lee W; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Min do S; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Kim H; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
  • Han G; Translational Research Center for Protein Function Control, Yonsei University, Seoul, Korea.
  • Choi KY; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Nat Chem Biol ; 12(8): 593-600, 2016 08.
Article en En | MEDLINE | ID: mdl-27294323

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiohidantoínas / Proteínas Proto-Oncogénicas p21(ras) / Proteínas RGS / Beta Catenina / Bibliotecas de Moléculas Pequeñas / Proteína Axina Límite: Animals / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2016 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiohidantoínas / Proteínas Proto-Oncogénicas p21(ras) / Proteínas RGS / Beta Catenina / Bibliotecas de Moléculas Pequeñas / Proteína Axina Límite: Animals / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2016 Tipo del documento: Article