Lymphocyte-activation gene-3, an important immune checkpoint in cancer.

He, Yayi; Rivard, Christopher J; Rozeboom, Leslie; Yu, Hui; Ellison, Kim; Kowalewski, Ashley; Zhou, Caicun; Hirsch, Fred R

He, Yayi; Rivard, Christopher J; Rozeboom, Leslie; Yu, Hui; Ellison, Kim; Kowalewski, Ashley; Zhou, Caicun; Hirsch, Fred R.

Afiliación

He Y; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China.
Rivard CJ; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Rozeboom L; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Yu H; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Ellison K; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kowalewski A; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Zhou C; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Hirsch FR; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, China. caicunzhoudr@163.com.

Cancer Sci ; 107(9): 1193-7, 2016 Sep.

Article en En | MEDLINE | ID: mdl-27297395

Asunto(s)

Antígenos CD/metabolismo; Inmunomodulación; Neoplasias/inmunología; Neoplasias/metabolismo; Animales; Anticuerpos Monoclonales/farmacología; Anticuerpos Monoclonales/uso terapéutico; Antígenos CD/genética; Antígeno B7-H1/metabolismo; Antígeno CTLA-4/metabolismo; Susceptibilidad a Enfermedades; Descubrimiento de Drogas; Expresión Génica; Humanos; Inmunomodulación/genética; Terapia Molecular Dirigida; Neoplasias/tratamiento farmacológico; Neoplasias/genética; Receptor de Muerte Celular Programada 1/metabolismo; Transducción de Señal/efectos de los fármacos; Subgrupos de Linfocitos T/inmunología; Subgrupos de Linfocitos T/metabolismo; Proteína del Gen 3 de Activación de Linfocitos

Palabras clave

Cancer checkpoints; clinical trial; immunotherapy; lymphocyte-activation gene-3; soluble LAG-3

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos CD / Inmunomodulación / Neoplasias Límite: Animals / Humans Idioma: En Revista: Cancer Sci Año: 2016 Tipo del documento: Article País de afiliación: China

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