Morphine and ketamine inhibit immune function of gastric cancer patients by increasing percentage of CD4(+)CD25(+)Foxp3(+) regulatory T cells in vitro.

Hou, Min; Zhou, Nai-Bao; Li, Hao; Wang, Bao-Sheng; Wang, Xiu-Qin; Wang, Xing-Wu; Wang, Kai-Guo; Xue, Fu-Shan

Morphine and ketamine inhibit immune function of gastric cancer patients by increasing percentage of CD4(+)CD25(+)Foxp3(+) regulatory T cells in vitro.

Hou, Min; Zhou, Nai-Bao; Li, Hao; Wang, Bao-Sheng; Wang, Xiu-Qin; Wang, Xing-Wu; Wang, Kai-Guo; Xue, Fu-Shan.

Afiliación

Hou M; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China; Medicine and Life Sciences College of Shandong Academy of Medical Sciences, Jinan University, Jinan, Shandong, China.
Zhou NB; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Li H; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Wang BS; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Wang XQ; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Wang XW; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Wang KG; Department of Anesthesiology, Shandong Cancer Hospital affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, China. Electronic address: wangkg666@163.com.
Xue FS; Department of Anesthesiology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: xuefushan@aliyun.com.

J Surg Res ; 203(2): 306-12, 2016 06 15.

Article en En | MEDLINE | ID: mdl-27363637

Asunto(s)

Analgésicos Opioides/efectos adversos; Anestésicos Disociativos/efectos adversos; Ketamina/efectos adversos; Morfina/efectos adversos; Neoplasias Gástricas/inmunología; Linfocitos T Reguladores/efectos de los fármacos; Anciano; Biomarcadores/metabolismo; Linfocitos T CD4-Positivos/efectos de los fármacos; Linfocitos T CD4-Positivos/metabolismo; Linfocitos T CD8-positivos/efectos de los fármacos; Linfocitos T CD8-positivos/metabolismo; Estudios de Casos y Controles; Relación Dosis-Respuesta a Droga; Femenino; Citometría de Flujo; Humanos; Masculino; Persona de Mediana Edad; Neoplasias Gástricas/sangre; Linfocitos T Reguladores/metabolismo

Palabras clave

CD4(+)/CD8(+) ratio; Gastric cancer; Ketamine; Morphine; Regulatory T cells

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Linfocitos T Reguladores / Analgésicos Opioides / Ketamina / Anestésicos Disociativos / Morfina Tipo de estudio: Observational_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Surg Res Año: 2016 Tipo del documento: Article País de afiliación: China

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