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Ebola Virus Epidemiology and Evolution in Nigeria.
Folarin, Onikepe A; Ehichioya, Deborah; Schaffner, Stephen F; Winnicki, Sarah M; Wohl, Shirlee; Eromon, Philomena; West, Kendra L; Gladden-Young, Adrianne; Oyejide, Nicholas E; Matranga, Christian B; Deme, Awa Bineta; James, Ayorinde; Tomkins-Tinch, Christopher; Onyewurunwa, Kenneth; Ladner, Jason T; Palacios, Gustavo; Nosamiefan, Iguosadolo; Andersen, Kristian G; Omilabu, Sunday; Park, Daniel J; Yozwiak, Nathan L; Nasidi, Abdusallam; Garry, Robert F; Tomori, Oyewale; Sabeti, Pardis C; Happi, Christian T.
Afiliación
  • Folarin OA; Department of Biological Sciences African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State.
  • Ehichioya D; Department of Biological Sciences African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State.
  • Schaffner SF; Department of Broad Institute of Harvard and MIT Department of FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge.
  • Winnicki SM; Department of Broad Institute of Harvard and MIT Department of FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge.
  • Wohl S; Department of Broad Institute of Harvard and MIT Department of FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge.
  • Eromon P; Department of Biological Sciences African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State.
  • West KL; Department of Broad Institute of Harvard and MIT.
  • Gladden-Young A; Department of Broad Institute of Harvard and MIT.
  • Oyejide NE; Department of Biological Sciences.
  • Matranga CB; Department of Broad Institute of Harvard and MIT.
  • Deme AB; Department de Parasitologie et Mycologie, Université Cheikh Anta Diop de Dakar, Fann, Dakar, Senegal.
  • James A; Department of Biochemistry.
  • Tomkins-Tinch C; Department of Broad Institute of Harvard and MIT.
  • Onyewurunwa K; Department of Biological Sciences African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State.
  • Ladner JT; Department of Center for Genome Sciences, US Army Medical Research Institute of Infectious Diseases, Frederick, Massachusetts.
  • Palacios G; Department of Center for Genome Sciences, US Army Medical Research Institute of Infectious Diseases, Frederick, Massachusetts.
  • Nosamiefan I; Department of Broad Institute of Harvard and MIT.
  • Andersen KG; Department of The Scripps Research Institute, Scripps Translational Science Institute, La Jolla, California.
  • Omilabu S; Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos.
  • Park DJ; African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State Department of Broad Institute of Harvard and MIT.
  • Yozwiak NL; African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State Department of Broad Institute of Harvard and MIT Department of FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge.
  • Nasidi A; Department of Nigeria Centre for Disease Control, Abuja.
  • Garry RF; African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
  • Tomori O; Department of Biological Sciences Department of Nigerian Academy of Science, Akoka-Yaba, Lagos.
  • Sabeti PC; African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State Department of Broad Institute of Harvard and MIT Department of FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge Department of Howar
  • Happi CT; Department of Biological Sciences African Center of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Osun State.
J Infect Dis ; 214(suppl 3): S102-S109, 2016 10 15.
Article en En | MEDLINE | ID: mdl-27377746
Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Brotes de Enfermedades / Genoma Viral / Fiebre Hemorrágica Ebola / Ebolavirus Tipo de estudio: Screening_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2016 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Brotes de Enfermedades / Genoma Viral / Fiebre Hemorrágica Ebola / Ebolavirus Tipo de estudio: Screening_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2016 Tipo del documento: Article