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Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.
Perales-Clemente, Ester; Cook, Alexandra N; Evans, Jared M; Roellinger, Samantha; Secreto, Frank; Emmanuele, Valentina; Oglesbee, Devin; Mootha, Vamsi K; Hirano, Michio; Schon, Eric A; Terzic, Andre; Nelson, Timothy J.
Afiliación
  • Perales-Clemente E; Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics, and Medical Genetics, Division of Cardiovascular Diseases, Mayo Clinic Center for Regenerative Medicine, Rochester, MN, USA.
  • Cook AN; Departments of Cardiovascular Diseases, Molecular Pharmacology and Experimental Therapeutics, Division of General Internal Medicine, Division of Pediatric Cardiology, and Transplant Center, Mayo Clinic Center for Regenerative Medicine, Rochester, MN, USA.
  • Evans JM; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  • Roellinger S; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Secreto F; Departments of Cardiovascular Diseases, Molecular Pharmacology and Experimental Therapeutics, Division of General Internal Medicine, Division of Pediatric Cardiology, and Transplant Center, Mayo Clinic Center for Regenerative Medicine, Rochester, MN, USA.
  • Emmanuele V; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
  • Oglesbee D; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Mootha VK; Department of Molecular Biology, Howard Hughes Medical Institute Massachusetts General Hospital, Boston, MA, USA.
  • Hirano M; Department of Neurology, Columbia University Medical Center, New York, NY, USA.
  • Schon EA; Department of Neurology, Columbia University Medical Center, New York, NY, USA Department of Genetics and Development, Columbia University Medical Center, New York, NY, USA.
  • Terzic A; Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics, and Medical Genetics, Division of Cardiovascular Diseases, Mayo Clinic Center for Regenerative Medicine, Rochester, MN, USA.
  • Nelson TJ; Departments of Cardiovascular Diseases, Molecular Pharmacology and Experimental Therapeutics, Division of General Internal Medicine, Division of Pediatric Cardiology, and Transplant Center, Mayo Clinic Center for Regenerative Medicine, Rochester, MN, USA nelson.timothy@mayo.edu.
EMBO J ; 35(18): 1979-90, 2016 09 15.
Article en En | MEDLINE | ID: mdl-27436875

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / ADN Mitocondrial / Diferenciación Celular / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: EMBO J Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / ADN Mitocondrial / Diferenciación Celular / Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: EMBO J Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos