Evaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promoter methylation and global DNA hypomethylation in type I and type II ovarian cancers.

Notaro, Sara; Reimer, Daniel; Fiegl, Heidi; Schmid, Gabriel; Wiedemair, Annamarie; Rössler, Julia; Marth, Christian; Zeimet, Alain Gustave

Notaro, Sara; Reimer, Daniel; Fiegl, Heidi; Schmid, Gabriel; Wiedemair, Annamarie; Rössler, Julia; Marth, Christian; Zeimet, Alain Gustave.

Afiliación

Notaro S; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Reimer D; Department of Gynecology and Obstetrics, University of Brescia, P.zza Spedali Civili 1, 25123, Brescia, Italy.
Fiegl H; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Schmid G; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Wiedemair A; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Rössler J; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Marth C; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Zeimet AG; Department of Obstetrics and Gynecology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

BMC Cancer ; 16: 589, 2016 08 02.

Article en En | MEDLINE | ID: mdl-27485273

Asunto(s)

Metilación de ADN; Receptor 1 de Folato/genética; Neoplasias Ováricas/tratamiento farmacológico; Neoplasias Ováricas/patología; Regulación hacia Arriba; Anciano; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Elementos de Nucleótido Esparcido Largo; Persona de Mediana Edad; Neoplasias Ováricas/genética; Platino (Metal)/uso terapéutico; Regiones Promotoras Genéticas; Estudios Retrospectivos; Análisis de Supervivencia

Palabras clave

FOLR1; FOLR1 promoter methylation; Folate receptor 1; Global DNA hypomethylation; Ovarian cancer; Platinum sensitivity; Type I; Type II

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Regulación hacia Arriba / Metilación de ADN / Receptor 1 de Folato Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Austria

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