[Determination of trace cobalt in human urine by graphite furnace atomic absorption spectrometr].

ABSTRACT

OBJECTIVE: To establish a method to determine cobalt in human urine by graphite furnace atomic absorption spectrometry. METHODS: Urine with 2% nitric acid diluted two-fold, to quantify the curve, graphite furnace atomic absorption spectrometric detection. RESULTS: Co was linear within 2.5~40.0 ng/ml with r>0.999. Spike experiment showed that Co received good recovery rate, which was 90.8%~94.8%. Intra-assay precisions were 3.2%~5.1% for Co, inter-assay precisions were 4.4%~5.2% for Co. CONCLUSION: The method by using graphite furnace atomic absorption spectrometr to determine urine Co was fast, accurate and with low matrix effect. It could meet the requirement in GBZ/T 210.5-2008.