Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture.

Miller, Bradley R; Drake, Eric J; Shi, Ce; Aldrich, Courtney C; Gulick, Andrew M

Miller, Bradley R; Drake, Eric J; Shi, Ce; Aldrich, Courtney C; Gulick, Andrew M.

Afiliación

Miller BR; From the Hauptman-Woodward Medical Research Institute, Buffalo, New York 14203.
Drake EJ; the Department of Structural Biology, University at Buffalo, Buffalo, New York 14203, and.
Shi C; From the Hauptman-Woodward Medical Research Institute, Buffalo, New York 14203.
Aldrich CC; the Department of Structural Biology, University at Buffalo, Buffalo, New York 14203, and.
Gulick AM; the Center for Drug Design and Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455.

J Biol Chem ; 291(43): 22559-22571, 2016 Oct 21.

Article en En | MEDLINE | ID: mdl-27597544

Asunto(s)

Escherichia coli/enzimología; Péptido Sintasas/química; Pseudomonas aeruginosa/enzimología; Escherichia coli/genética; Péptido Sintasas/genética; Péptido Sintasas/metabolismo; Dominios Proteicos; Pseudomonas aeruginosa/genética

Palabras clave

acyl carrier protein (ACP); bacterial metabolism; enzyme mechanism; enzyme mutation; multifunctional protein; natural product biosynthesis; siderophore; structural biology

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptido Sintasas / Pseudomonas aeruginosa / Escherichia coli Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article

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