Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors.

Yadlapalli, Jai Shankar K; Ford, Benjamin M; Ketkar, Amit; Wan, Anqi; Penthala, Narasimha R; Eoff, Robert L; Prather, Paul L; Dobretsov, Maxim; Crooks, Peter A

Yadlapalli, Jai Shankar K; Ford, Benjamin M; Ketkar, Amit; Wan, Anqi; Penthala, Narasimha R; Eoff, Robert L; Prather, Paul L; Dobretsov, Maxim; Crooks, Peter A.

Afiliación

Yadlapalli JSK; Departments of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Ford BM; Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Ketkar A; Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Wan A; Departments of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Penthala NR; Departments of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Eoff RL; Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Prather PL; Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Dobretsov M; Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Crooks PA; Departments of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address: pacrooks@uams.edu.

Pharmacol Res ; 113(Pt A): 335-347, 2016 11.

Article en En | MEDLINE | ID: mdl-27637375

Asunto(s)

Analgésicos/farmacología; Derivados de la Morfina/farmacología; Morfina/farmacología; Receptores Opioides delta/metabolismo; Receptores Opioides mu/metabolismo; Analgésicos Opioides/metabolismo; Animales; Células CHO; Línea Celular; Cricetinae; Cricetulus; Diabetes Mellitus Experimental/complicaciones; Tolerancia a Medicamentos/fisiología; Masculino; Dolor/tratamiento farmacológico; Dolor/etiología; Ratas; Ratas Sprague-Dawley; Receptores Opioides kappa/metabolismo

Palabras clave

3-Isobutyl-1-methylxanthine (PubChem CID3758); 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid (PubChem CID23831); Antinociception; DPDPE (PubChem CID104787); Ethylenediaminetetraacetic acid (PubChem CID9902403); Morphine; Morphine-6-O-sulfate; Naltrexone hydrochloride (PubChem CID 5485201); Naltrindole hydrochloride (Pubchem CID16219715); Norbinaltorphimine hydrochloride (PubChem CID11957626); Opioid receptors; Streptozotocin (Pubchem CID2733335); Streptozotocin-induced diabetes; [D-Ala(2),N-MePhe(4),Gly-ol]enkephalin (PubChem CID5462471)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Opioides delta / Receptores Opioides mu / Analgésicos / Morfina / Derivados de la Morfina Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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