Dipotassium N-stearoyltyrosinate ameliorated pathological injuries in triple-transgenic mouse model of Alzheimer's disease.

Liu, Sha; Tang, Shuang-Qi; Cui, Heng-Jing; Yin, Sha; Yin, Ming; Zhao, Hong; Meng, Ling-Hua; Wang, Ze-Jian; Lu, Yang

Dipotassium N-stearoyltyrosinate ameliorated pathological injuries in triple-transgenic mouse model of Alzheimer's disease.

Liu, Sha; Tang, Shuang-Qi; Cui, Heng-Jing; Yin, Sha; Yin, Ming; Zhao, Hong; Meng, Ling-Hua; Wang, Ze-Jian; Lu, Yang.

Afiliación

Liu S; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China.
Tang SQ; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China.
Cui HJ; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China.
Yin S; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China.
Yin M; School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China.
Zhao H; School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China.
Meng LH; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China.
Wang ZJ; School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, China. Electronic address: wangzejian@sjtu.edu.cn.
Lu Y; Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, China. Electronic address: luyangssmu@163.com.

J Pharmacol Sci ; 132(1): 92-99, 2016 Sep.

Article en En | MEDLINE | ID: mdl-27671351

Asunto(s)

Enfermedad de Alzheimer/tratamiento farmacológico; Fármacos Neuroprotectores/uso terapéutico; Tirosina/análogos & derivados; Enfermedad de Alzheimer/metabolismo; Péptidos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/genética; Animales; Encéfalo/efectos de los fármacos; Encéfalo/metabolismo; Caspasa 3/metabolismo; Citocinas/metabolismo; Modelos Animales de Enfermedad; Masculino; Aprendizaje por Laberinto/efectos de los fármacos; Ratones Endogámicos C57BL; Ratones Transgénicos; Fármacos Neuroprotectores/farmacología; Presenilina-1/genética; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Tirosina/farmacología; Tirosina/uso terapéutico; Proteína X Asociada a bcl-2/metabolismo; Proteínas tau/genética; Proteínas tau/metabolismo

Palabras clave

APP(SWE)/PS1(M146V)/Tau(P301L) mouse model; Alzheimer's disease; Animal behavior; Dipotassium N-stearoyltyrosinate; Neuroprotection

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tirosina / Fármacos Neuroprotectores / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google