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The variability in beta-cell function in placebo-treated subjects with type 2 diabetes: application of the weight-HbA1c-insulin-glucose (WHIG) model.
Duong, Janna K; de Winter, Willem; Choy, Steve; Plock, Nele; Naik, Himanshu; Krauwinkel, Walter; Visser, Sandra A G; Verhamme, Katia M; Sturkenboom, Miriam C; Stricker, B H; Danhof, Meindert.
Afiliación
  • Duong JK; Department of Medical Informatics, Erasmus Medical Centre, Rotterdam, the Netherlands.
  • de Winter W; Leiden Academic Centre for Drug Research (LACDR), Division of Pharmacology, Leiden University, Leiden, the Netherlands.
  • Choy S; Faculty of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
  • Plock N; Janssen Prevention Center, Leiden, the Netherlands.
  • Naik H; Department of Pharmaceutical Biosciences, Pharmacometrics Research Group, Uppsala University, Uppsala, Sweden.
  • Krauwinkel W; Global Pharmacometrics, Takeda Pharmaceuticals International, Zurich and Deerfield, Switzerland and USA.
  • Visser SA; Global Pharmacometrics, Takeda Pharmaceuticals International, Zurich and Deerfield, Switzerland and USA.
  • Verhamme KM; Quantitative Pharmacology, Biogen, Cambridge, MA, USA.
  • Sturkenboom MC; Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Europe BV, Leiden, the Netherlands.
  • Stricker BH; Early Stage Quantitative Pharmacology & Pharmacometrics, Merck, Upper Gwynedd, PA, USA.
  • Danhof M; Department of Medical Informatics, Erasmus Medical Centre, Rotterdam, the Netherlands.
Br J Clin Pharmacol ; 83(3): 487-497, 2017 03.
Article en En | MEDLINE | ID: mdl-27679422

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucemia / Peso Corporal / Hemoglobina Glucada / Resistencia a la Insulina / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Insulina Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glucemia / Peso Corporal / Hemoglobina Glucada / Resistencia a la Insulina / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Insulina Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos