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A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Wrasidlo, Wolfgang; Tsigelny, Igor F; Price, Diana L; Dutta, Garima; Rockenstein, Edward; Schwarz, Thomas C; Ledolter, Karin; Bonhaus, Douglas; Paulino, Amy; Eleuteri, Simona; Skjevik, Åge A; Kouznetsova, Valentina L; Spencer, Brian; Desplats, Paula; Gonzalez-Ruelas, Tania; Trejo-Morales, Margarita; Overk, Cassia R; Winter, Stefan; Zhu, Chunni; Chesselet, Marie-Francoise; Meier, Dieter; Moessler, Herbert; Konrat, Robert; Masliah, Eliezer.
Afiliación
  • Wrasidlo W; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Tsigelny IF; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Price DL; 2 San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA.
  • Dutta G; 3 Neuropore Therapies, Inc., San Diego, CA 92121, USA.
  • Rockenstein E; 4 Department of Neurology, University of California, Los Angeles, CA, 90095-1769, USA.
  • Schwarz TC; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Ledolter K; 5 MFPL and University of Vienna, Vienna, Austria.
  • Bonhaus D; 5 MFPL and University of Vienna, Vienna, Austria.
  • Paulino A; 3 Neuropore Therapies, Inc., San Diego, CA 92121, USA.
  • Eleuteri S; 3 Neuropore Therapies, Inc., San Diego, CA 92121, USA.
  • Skjevik ÅA; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Kouznetsova VL; 2 San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA.
  • Spencer B; 6 Department of Biomedicine, University of Bergen, N-5009 Bergen, Norway.
  • Desplats P; 7 Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
  • Gonzalez-Ruelas T; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Trejo-Morales M; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Overk CR; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Winter S; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Zhu C; 1 Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.
  • Chesselet MF; 8 EVER Neuropharma, Unterach, Austria.
  • Meier D; 4 Department of Neurology, University of California, Los Angeles, CA, 90095-1769, USA.
  • Moessler H; 4 Department of Neurology, University of California, Los Angeles, CA, 90095-1769, USA.
  • Konrat R; 3 Neuropore Therapies, Inc., San Diego, CA 92121, USA.
  • Masliah E; 8 EVER Neuropharma, Unterach, Austria.
Brain ; 139(Pt 12): 3217-3236, 2016 12.
Article en En | MEDLINE | ID: mdl-27679481
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Conducta Animal / Alfa-Sinucleína / Descubrimiento de Drogas / Antiparkinsonianos Límite: Animals / Humans Idioma: En Revista: Brain Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Conducta Animal / Alfa-Sinucleína / Descubrimiento de Drogas / Antiparkinsonianos Límite: Animals / Humans Idioma: En Revista: Brain Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos