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Anti-PD-1 inhibits Foxp3+ Treg cell conversion and unleashes intratumoural effector T cells thereby enhancing the efficacy of a cancer vaccine in a mouse model.
Dyck, Lydia; Wilk, Mieszko M; Raverdeau, Mathilde; Misiak, Alicja; Boon, Louis; Mills, Kingston H G.
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  • Dyck L; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland.
  • Wilk MM; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland.
  • Raverdeau M; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland.
  • Misiak A; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland.
  • Boon L; Bioceros, Utrecht, The Netherlands.
  • Mills KH; Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland. kingston.mills@tcd.ie.
Cancer Immunol Immunother ; 65(12): 1491-1498, 2016 12.
Article en En | MEDLINE | ID: mdl-27680570
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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Vacunas contra el Cáncer / Factores de Transcripción Forkhead Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2016 Tipo del documento: Article País de afiliación: Irlanda
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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Vacunas contra el Cáncer / Factores de Transcripción Forkhead Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2016 Tipo del documento: Article País de afiliación: Irlanda