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ddpcr: an R package and web application for analysis of droplet digital PCR data.
Attali, Dean; Bidshahri, Roza; Haynes, Charles; Bryan, Jennifer.
Afiliación
  • Attali D; Bioinformatics Training Program, University of British Columbia, Vancouver, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada.
  • Bidshahri R; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada; Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, Canada.
  • Haynes C; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada; Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, Canada.
  • Bryan J; Michael Smith Laboratories, University of British Columbia, Vancouver, Canada; Department of Statistics, University of British Columbia, Vancouver, Canada.
F1000Res ; 5: 1411, 2016.
Article en En | MEDLINE | ID: mdl-27703666
Droplet digital polymerase chain reaction (ddPCR) is a novel platform for exact quantification of DNA which holds great promise in clinical diagnostics. It is increasingly popular due to its digital nature, which provides more accurate quantification and higher sensitivity than traditional real-time PCR. However, clinical adoption has been slowed in part by the lack of software tools available for analyzing ddPCR data. Here, we present ddpcr - a new R package for ddPCR visualization and analysis. In addition, ddpcr includes a web application (powered by the Shiny R package) that allows users to analyze ddPCR data using an interactive graphical interface.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: F1000Res Año: 2016 Tipo del documento: Article País de afiliación: Canadá

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: F1000Res Año: 2016 Tipo del documento: Article País de afiliación: Canadá