MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes.

Suresh Babu, Sahana; Thandavarayan, Rajarajan A; Joladarashi, Darukeshwara; Jeyabal, Prince; Krishnamurthy, Shashirekha; Bhimaraj, Arvind; Youker, Keith A; Krishnamurthy, Prasanna

Suresh Babu, Sahana; Thandavarayan, Rajarajan A; Joladarashi, Darukeshwara; Jeyabal, Prince; Krishnamurthy, Shashirekha; Bhimaraj, Arvind; Youker, Keith A; Krishnamurthy, Prasanna.

Afiliación

Suresh Babu S; Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Thandavarayan RA; Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Joladarashi D; Department of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham, AL 35294, USA.
Jeyabal P; Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Krishnamurthy S; Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.
Bhimaraj A; Houston Methodist DeBakey Heart &Vascular Center, Houston Methodist Hospital, Houston, Texas, USA.
Youker KA; Houston Methodist DeBakey Heart &Vascular Center, Houston Methodist Hospital, Houston, Texas, USA.
Krishnamurthy P; Department of Cardiovascular Sciences, Centre for Cardiovascular Regeneration, Houston Methodist Research Institute, Houston, TX 77030, USA.

Sci Rep ; 6: 36207, 2016 11 09.

Article en En | MEDLINE | ID: mdl-27827458

Asunto(s)

Proteínas ADAM/genética; Diabetes Mellitus Experimental/genética; Macrófagos/citología; Proteínas de la Membrana/genética; MicroARNs/genética; Miocitos Cardíacos/citología; Regiones no Traducidas 3'; Animales; Apoptosis; Regulación de la Expresión Génica/efectos de los fármacos; Glucosa/farmacología; Humanos; Macrófagos/efectos de los fármacos; Ratones; Fagocitosis; Proto-Oncogenes Mas; Células RAW 264.7; Células THP-1; Tirosina Quinasa c-Mer/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Miocitos Cardíacos / MicroARNs / Diabetes Mellitus Experimental / Proteínas ADAM / Macrófagos / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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